HORDB

ID: hor001919
Uniprot ID: P41585
Protein name: Growth hormone-releasing factor
Gene name: NA
Organism: Oncorhynchus nerka (Sockeye salmon) (Salmo nerka)
Family: Glucagon family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Oncorhynchus (genus), Salmoninae (subfamily), Salmonidae (family), Salmoniformes (order), Protacanthopterygii, Euteleosteomorpha (cohort), Clupeocephala, Osteoglossocephalai, Teleostei (infraclass), Neopterygii (subclass), Actinopteri (class), Actinopterygii (superclass), Euteleostomi, Teleostomi, Gnathostomata, Vertebrata, Craniata (subphylum), Chordata (phylum), Deuterostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: GO:0005179 hormone activity; GO:0005184 neuropeptide hormone activity
GO BP: GO:0007165 signal transduction
GO CC: GO:0005576 extracellular region

Sequence: HADGMFNKAYRKALGQLSARKYLHSLMAKRVGGGSTMEDDTEPLS
Length: 45(82-126)
Propeptide: MSSKATLALLIYGIIMHYSVYSSPLGLNYPNLRLENEVYDEDGNSLPALAFDSDQIAIRSPPSVADDLYTLYYPPEKGTERHADGMFNKAYRKALGQLSARKYLHSLMAKRVGGGSTMEDDTEPLSKRHSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYRQRYRNKGRRLGYL
Signal peptide: MSSKATLALLIYGIIMHYSVYS
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001919_AF2.pdb

hor001919_ESM.pdb

Mass:	572463	Formula:	C212H342N64O66S3
Absent amino acids:	CIW	Common amino acids:	AGL
pI:	9.81	Basic residues:	9
Polar residues:	14	Hydrophobic residues:	12
Hydrophobicity:	-66.89	Boman Index:	-9484
Half-Life:	3.5 hour	Half-Life Yeast:	10 min
Half-Life E.Coli:	>10 hour	Aliphatic Index	60.89
Instability Index:	3248	Extinction Coefficient cystines:	2980
Absorbance 280nm:	67.73